Three Dacorum householders will join 17 others who are tackling the London Marathon on Sunday to raise money for Rennie Grove Hospice Care.
They will aim to raise £2,000 each for the charity, which has nurses in Tring who travel to treat terminally ill patients in their own homes.
Hemel Hempstead marathoner Sam Hawkridge said: “Last year, my auntie-in-law passed away from cancer, and thanks to the hospice at home nurses she was able to be at home.
“The nursing care and support was second to none, and I am running the marathon to raise as much money as possible to help ensure that other patients and families can benefit from this fantastic service.
“I love running, so this seemed like the perfect way to give back to the charity.”
Rennie Grove runner Richard Lambert, from Tring, will take on the challenge after it helped his family when his mother-in-law was terminally ill in 2009.
He said: “I ran the 2010 London Marathon and successfully achieved my goal of beating the bloke in the Rhino costume!
“But this year, I’ve set my sights a bit higher and want to break the 5 hour barrier.
“Training has been going really well. I’m in a lucky position because my wife Adele is a Personal Trainer, so she’s been helping me out.”
Tring’s Sue Cox will run for Rennie Grove in memory of her uncle, who passed away last month.
She said: “The nurses have cared for my grandparents and my uncle, so I have seen first-hand the remarkable work that they do and I know how valuable they are to local patients and their families.
“It will be an emotional day, but I’ve got a fantastic support base and I know the money raised will make a big difference.”