A lorry collided with a vehicle before crashing into the central reservation on the M1 this afternoon (Tuesday, May 10).
Police were called at around 2pm to reports of an incident on the M1 southbound, between junctions 10 and 9.
A lorry is thought to have been in collision with a vehicle before striking the central reservation.
Officers are currently on scene alongside the fire and ambulance services.
A full closure is in place on the southbound carriageway between junctions 11 and 9 and is expected to remain for some time.
Motorists are therefore advised to avoid the area.
At this stage it is believed that the lorry driver may have suffered a medical episode and is being taken to hospital.